Two other DLBCL cases (16.7%) had HBs and HBe antigens, but this prevalence was not significantly higher than in cases of systemic IVLBCL (one of 11, 9.1%), nodal DLBCL (one of 54, 1.9%), or colon cancer (seven of 445, 1.6%). The gene discussed is HBE1; the disease is malignant colon neoplasm.