ZEB2 and hepatocellular carcinoma: In summary, our results provide interesting and new information that overexpression of cytoplasmic ZEB2 in HCC and peritumoral liver tissues may be important in the acquisition of a favorable phenotype, suggesting that overexpression of cytoplasmic ZEB2 by peritumoral liver tissues, as detected by IHC, may predict the postoperative survival of patients with HCC, and it might be a helpful criterion to optimize individual therapeutic management.