AKT1 and schizophrenia: An influential article by Emamian et al. [12] showed a 68% reduction of AKT1 protein levels in lymphocyte-derived cell lines of schizophrenia patients, and presented several additional converging lines of evidence suggesting involvement of AKT1 in schizophrenia, including disturbed prepulse inhibition in AKT−/− mice, decreased expression of AKT1 in post-mortem brains of schizophrenia patients, and association of AKT1 variants with schizophrenia.