MDA-MB-231 cells are metastatic breast cancer cells that express multiple zinc finger transcriptional repressors, including Snai1 (Figure S1), Snai2, Zeb1 and Zeb2, all of which can bind Eboxes in the E-cadherin promoter and regulate EMT [32], [33], [34]. The gene discussed is CDH1; the disease is breast cancer.