Smith et al. [45] reported that MYC-expressing CD4+ T cells in the VavP-Myc model was more prone to apoptosis than the corresponding CD4+/CD8+ T-cells, suggesting that FLIPL might contribute to increased survival of this population in our model system, although this did not contribute to increased T-cell lymphoma over AML ratio. Here, CD4 is linked to acute myeloid leukemia.