However, western blot analysis of D54 glioblastoma cell lines showed only slightly lowered expression of Kir2.1, normal expression of Kir4.1, and increased expression of Kir2.3 and Kir3.1 as compared to normal astrocytes, while electrophysiological recording found no Kir current. Here, KCNJ10 is linked to glioblastoma.