ABCD2 and stroke disorder: Similarly, Yang et al. in 2010 showed that ABCD2 score > 4 was found to be an independent risk factor for long-term risk of stroke (up to 3 years) (HR, 2.27; 95% CI, 1.36 to 3.80) and for death (hazard ratio, 1.68; 95% CI, 0.99 to 2.85).