We did not detect CNVs (including common variants) that affect the well-confirmed AD loci reported by large GWAS (CLU, PICALM, BIN1, CR1, MS4A4/MS4A6E, CD2AP, CD33, EPHA1, and ABCA7) (Harold et al. 2009; Lambert et al. 2009; Carrasquillo et al. 2010; Hollingworth et al. 2011; Naj et al. 2011). This evidence concerns the gene PICALM and Alzheimer disease.