Among the catalogued ALS-like motor neuron diseases, mutations in SOD1 (ALS1), FUS/TLS (ALS6), VAPB (ALS8), ANG (ALS9), TARDBP (ALS10), FIG4 (ALS11) and a hexanucleotide-repeat expansion (GGGGCC) in the C9ORF72 cause adult onset neurodegenerative disorder [2]–[4]. The gene discussed is TARDBP; the disease is amyotrophic lateral sclerosis.