Interestingly, in one of the CML-like cases, the breakpoints in BCR and JAK2 were the same as in our case, whereas in the AML case the breakpoint in BCR was similar to that of p210 BCR/ABL and was in exon 11 for JAK2. Unlike our case, the patients in the cases mentioned above died after developing a blast crisis. The gene discussed is JAK2; the disease is acute myeloid leukemia.