Most interestingly, we observed a high frequency of the polymorphism F144I in published sequences of LMP1 from EBV associated tumors: 5/5 variants isolated from Vietnamese patients with NPC [40], 21/21 variants isolated from patients with NPC in the southern China [41], 7/7 variants isolated from patients with nasal NK/T-cell lymphoma [42], 5/5 variants from NPC in Hong Kong [43], and in 10/12 variants isolated from salivary gland lymphoepithelial carcinoma [44]. This evidence concerns the gene PDLIM7 and nasopharyngeal carcinoma.