GRK2 and infection: Similar results were also obtained when comparing the effects of IL-13 on c-SrcTyr416 and ERK1/2 phosphorylation in HASM cells at 24 hr following transfection with either an adenovirus vector expressing lacZ (adeno-LacZ), serving as a negative control, or adeno-βARK-ct, which encodes the C-terminal domain of βARK1 that was shown to block Gβγ signaling [14], [15], both at a multiplicity of infection (MOI) of 100.