Notably, only aTOH1 with OR of 0.5 (Table 2), was derived from parent cTOH3 (2p16.3–16.1) where both cTOH3 and aTOH1 are significantly under-represented in lung-cancer cases compared to controls (OR = 0.69 and 0.5, p = 0.001 and 0.005, respectively; Figure 2, Tables 1 and 2). This evidence concerns the gene ATOH1 and lung cancer.