The composite score values obtained for Ser473-pAkt and NF-kB p65 expression in PC specimens (3.3±0.4 and 2.7±0.3) were significantly enhanced as compared to the value for normal prostate tissues (0.3±0.1 and 0.3±0.2; p<0.0001), respectively (Figure 2b and c). Here, NFKB1 is linked to pachyonychia congenita.