More specifically, a positive immunoreactivity was observed for EGFR and its phosphorylated Tyr1173-pEGFR activated form, Ser473-pAkt and MIC-1 in the cytoplasm and near or at the cell surface in intermediate and luminal PC cells detected in prostatic adenocarcinoma specimens (Figure 4 and Figure S1). This evidence concerns the gene EGFR and prostate adenocarcinoma.