PAX6 and cataract: In general, glycosylation is shown to play a role in intra- and intercellular trafficking, molecular and cellular matrix interactions, initiation of signal transduction and in the regulation of processes such as cell growth, migration, differentiation and tumor invasion [74], [76] Interestingly, Gcnt2 is associated with cataracts – a well known feature of mutant Pax6 phenotype [77].