In the combined analysis that included the discovery and extension phases, the risk estimate of SRC rs6122566 in the recessive model was significantly associated with gastric cancer in both the pooled and meta-analyses (OR = 3.96, [95% CI: 2.05–7.65]; OR = 4.59, [95% CI: 2.74–7.70], respectively). This evidence concerns the gene SRC and gastric cancer.