Similar CTIP2 upregulation has been reported in epidermis of hyperproliferative diseases such as atopic dermatitis (AD) and allergic contact dermatitis (ACD) [45], supporting our assumption that Ctip2 function is implicated in epidermal regeneration and re-establishment of skin homeostasis under pathological conditions. The gene discussed is BCL11B; the disease is granular corneal dystrophy type II.