HF stem cell markers such as Nuclear factor of activated T-cells, cytoplasmic 1 (NFATc1), CD34 and Prominin-1/CD133 are all known to contribute in regulating epidermal stem cell quiescence, location, proliferation, wound healing and in tumor formation [31], [32], [33], [34], [35], [36], [37]. Here, PROM1 is linked to neoplasm.