Interestingly, previous studies indicated that the production of FGFs, particularly FGF10 and FGF18, is stimulated downstream of canonical Wnt signaling during certain cellular processes, such as chick embryo development, bone development and human hepatocellular carcinoma [30]–[32], raising the possibility that the enhanced β-catenin signaling seen in uterine stromal cells of Msx1d/dMsx2d/d mice may drive the increased FGF synthesis in these cells. This evidence concerns the gene FGF10 and hepatocellular carcinoma.