MYC and osteosarcoma: A recent study which identified a signature of 135 genes discriminating radiation-induced sarcomas (leiomyosarcomas, osteosarcomas, and ASs) from sporadic sarcomas did not include MYC as part of this signature; the only function found to be significantly deregulated between the two groups being mitochondria (Hadj-Hamou et al., 2011).