This observation is in contrast with a previous investigation [25] in which pERK expression was not correlated with tumor stage, whereas there are other studies in various other tumors (breast, pancreatic, endometrial and ovarian cancer) that have failed to substantiate a positive correlation between pERK expression and classical clinicopathological parameters [26,32,35-37]. Here, EIF2AK3 is linked to ovarian carcinoma.