Co-incubation of 14.G2a-28ζ transduced T cells with the GD2-positive Ewing sarcoma cell lines TC-71 and VH-64, but not the GD2-negative rhabdomyosarcoma cell line A-204 induced production of IFN-γ and TNF-α (Figure 3A). The gene discussed is TNF; the disease is rhabdomyosarcoma.