In order to address the question, whether dual inhibition of DPIV- and APN-like protease activities supports neuronal cell survival after transient cerebral ischemia, IPC1755, an inhibitor of DPIV/DPIV-like and APN/cAAP protease activity (Figure 6, see Materials for reference and protease-specific IC50 values), was administered icv ipsilateral to eMCAO. This evidence concerns the gene ANPEP and transient ischemic attack.