Most of these genes belonged to three functional categories: immune and inflammatory responses, such as IL-4, IL-8, TNFAIP6, and PTGS2; lipid and glucose metabolism, such as ABCA1, OSBP2, and GOS2; and organismal injury and abnormalities, such as APOBEC3A. Thus, these genes might be the genetic signatures for T2D. Here, PTGS2 is linked to type 2 diabetes mellitus.