Some selected genes with high discriminative ability, belonging to three cancer-relevant pathways, such as ATP-binding cassette (ABC) family of genes (ABCA4, ABCA8 [58]) were identified as prospective gene markers of lung AC [21] other one (ABCB1, ABCC3 and ABCF2) should be also under serious consideration. The gene discussed is ABCA4; the disease is cancer.