Proteolytic cleavage products of ATXN7 have been found in SCA7 patients as well as in transgenic models, and caspase-7 cleavage of ATXN7 at amino acids 266 and 344 has been identified (Garden et al. 2002; Young et al. 2007; Yvert et al. 2001). The gene discussed is ATXN7; the disease is spinocerebellar ataxia 7.