Molecular analyses of the Rdl gene of the Anopheles malaria vectors collected in 10 endemic areas of Indonesia: Aceh, North Sumatra, Bangka Belitung, Lampung, Central Java, East Nusa Tenggara, West Nusa Tenggara, West Sulawesi, Molucca and North Molucca indicated a high sequence conservation at the protein levels to the previously published Rdl sequence [25]. The gene discussed is LEO1; the disease is malaria.