Other non-organ-specific autoantibodies (SSA, SSB) are also commonly seen in NMO patients, and systemic autoimmune disorders such as Sjogren's Syndrome (SS) and systemic lupus erythematous (SLE) can occur concomitantly with NMO, which likely reflects an underlying predisposition for these patients to develop autoimmune disorders. This evidence concerns the gene SSB and synovial sarcoma.