Other non-organ-specific autoantibodies (SSA, SSB) are also commonly seen in NMO patients, and systemic autoimmune disorders such as Sjogren's Syndrome (SS) and systemic lupus erythematous (SLE) can occur concomitantly with NMO, which likely reflects an underlying predisposition for these patients to develop autoimmune disorders. Here, SSB is linked to neuromyelitis optica.