In a hospital-based case-control study from China, a somewhat lower prevalence of the slow-coding ADH1B*1/1 genotype was observed in patients with premature coronary artery disease (CAD) as compared to patients with late onset CAD (6.6% vs. 12.3%; p = 0.064) [45]. The gene discussed is ADH1B; the disease is Premature coronary artery atherosclerosis.