In response to opsonised IE, HIV-1 infection significantly reduced IL-6 release (1,116 pg/mL (IQR: 352–3,387) compared to 1,552 pg/mL (IQR: 889–6,331); p = 0.0078) and IL-1β release (16 pg/mL (IQR: 7–21) compared to 33 pg/mL (IQR: 27–65); p = 0.0078) from mock-infected IFNγ primed MDM (Figure 2A and 2C). This evidence concerns the gene IFNG and HIV-1 infection.