No loss in expression could be found between early (I/II) and advanced (III/IV) FIGO stages (p = 0.86; data not shown), but SFRP4 tissue expression decreased with loss of cancer differentiation showing significantly lower levels in undifferentiated compared to well differentiated cancers (p = 0.006 overall; G1 vs. G2, p = 0.004; G1 vs. G3, p = 0.017; data not shown). This evidence concerns the gene SFRP4 and cancer.