DPEP1 expression was decreased (T: N ratio of 0.1 in test cohort and 0.16 in validation cohort, P<0.01) and TPX2 expression was increased (T: N ratio of 2.14 in test cohort and 2.2 in validation cohort, P<0.001) in human pancreatic tumor tissues, as compared with surrounding non-tumor tissues in both cohorts (Figure 1, 2). This evidence concerns the gene DPEP1 and neoplasm.