KIF11 and Familial prostate cancer: Different mitotic kinesins serve specific functions, and the role of these proteins in prostate cancer has only been explored with respect to the most well-established member of this family, kinesin spindle protein (KIF11/Eg5), whose silencing has been shown to inhibit the growth of LNCaP and PC3 cell lines in vitro and in vivo[24], [25].