In addition, exon 3 of AKT3 harbouring the E17 hotspot locus was sequenced in 8 MCC cell lines (UiSo, MCC13, MCC26, MKL-1, LoKe, WaGa, HeRo, MaTi, BroLi), but did not reveal any mutations. The gene discussed is AKT3; the disease is Merkel cell skin cancer.