When we compared protein levels between HF (n = 74) and CNT (n = 9) hearts, the average of Ca+2 handling proteins (CaM and CaN) was significantly increased in pathological samples (112±3 vs. 100±6; 120±5 vs. 100±3; p<0.05 in both, when normalized to β-actin). The gene discussed is NUP214; the disease is hydrops fetalis.