CXCL8 and chronic obstructive pulmonary disease: In addition protein levels were increased in the supernatants from the fibroblasts in COPD group compared with control group for IL-6 ((993.0 ± 738.9) pg/mL versus (241.5 ± 148.4) pg/mL, P = 0.012, Figure 1(c)) and for IL-8 ((703.1 ± 278.0) pg/mL versus (165.0 ± 77.5) pg/mL, P < 0.001, Figure 2(c)).