Despite detection of immunoproteasome proteins LMP 2 and LMP 7 by western blot and of MECL-1 by 2-D gelelectrophoresis it remains unclear whether it is pure immunoproteasome and/or intermediate-type proteasomes that are found in the extracellular alveolar space of ARDS patients. The gene discussed is PSMB10; the disease is acute respiratory distress syndrome.