Using CES-D score rather than antidepressant use as a surrogate for depression, adjustment for forced expiratory volume/height2 instead of history of respiratory disease, exclusion of NSAIDs users (N = 320), or participants with CRP level greater than 10 g/L (N = 103) on the day of examination led to conclusions similar to those in main analyses. The gene discussed is CRP; the disease is major depressive disorder.