CD8A and neoplasm: Fig. 7C shows that in FTY720-treated recipients, there was a dramatic decrease in the number of donor WT CD8+ T cells migrating into the tumor, indicating that tumor infiltrating donor cells egress from the draining lymph node of the recipient. Taken together with observations in Fig. 6E, these data suggest that in the absence of functional selectin ligands on CD8+ T cells, the egress of cells from lymph node into the peripheral tumor is impaired.