Lastly, progressive lobular inflammatory activity was not associated with HOMA-IR (p = 0.065) (Figure 2C) or insulin resistance (p = 0.120), but was associated with older age (p = 0.001), AST (p<0.001) and ALT serum levels (p<0.001), as well as higher prevalence of the metabolic syndrome (p = 0.031). The gene discussed is GPT; the disease is Insulin resistance.