Similarly, there was a statistical positive association between fibrosis stage and higher levels of γ-GT (p = 0.003), insulin (p = 0.006) (Figure 2) and HOMA-IR (p = 0.005) (Figure 2B), as well as progressively higher prevalence of insulin resistance (p = 0.009) and the metabolic syndrome (p = 0.029). This evidence concerns the gene INS and Insulin resistance.