Several miR-214 targets have been characterized in various tumor types (ovarian cancer, cervical cancer and melanoma) including MEK3, JNK1 [29], PTEN [28], [36], Plexin-B1 [27], Ezh2 [35], [37], and TFAP2C [26] and so on. The gene discussed is PLXNB1; the disease is ovarian cancer.