GNAQ and infection: To determine whether EGL-30 (Gαq) signaling was sufficient to induce the Dar response in the absence of infection we generated transgenic animals that expressed constitutively active EGL-30(Q205L) in adult animals (using a heat shock-inducible promoter) or in the rectal epithelial cells (using a 1.3 Kb fragment of the egl-5 promoter).