GNAQ and infection: Both the Gαq-RhoGEF Trio-RHO-1 and Ras signaling pathways act upstream of LIN-45 (Raf) to mediate the immune response to infection, however, chromosomal gain-of-function mutations in EGL-30 (Gαq) or LET-60 (Ras) were not Dar suggesting that levels of signalling from these mutations was not individually sufficient to trigger the immune response.