Following virus infection, actin levels were upregulated, along with translocation of viral RNA recognition components to the mitochondria, including retinoic acid‐inducible protein I (RIG-I), tumor necrosis factor receptor-1 (TNFR1)-associated death domain protein (TRADD), tripartite motif protein 25 (TRIM25), and IKKε (inducible IκB kinase) [59]. This evidence concerns the gene TNFRSF1A and viral infectious disease.