Although a good correlation has been observed between genotype and phenotype—R555W in GCD1, R124C in LCD1, R124H in GCD2, R124L in RBCD, and R555Q in TBCD—some families having corneal dystrophies with TGFBI mutations have been reported to have variant phenotypes [10,11]. The gene discussed is TGFBI; the disease is corneal dystrophy.