The association between rs6050 and DVT remained statistically significant after adjustment for age, gender and plasmatic levels of fibrinogen (p = 0.0001, OR 1.39; 95% CI, 1.10-1.74); and for age, gender, fibrinogen levels, body mass index, FVL and prothrombin G20210A (p < 0.0001, OR 1.41; 95% CI, 1.10-1.81). Here, F2 is linked to deep vein thrombosis.