Analysis of microRNA expression of NK-AML samples demonstrated a clear pattern of clustered expression according to NPM1 mutational status, with three microRNAs over-expressed in NPM1mut-AML (miR-10a, let-7b and let-7c) and two microRNAs under-expressed (miR-130a and miR-335) (Figure 1A and 1B). Here, NPM1 is linked to acute myeloid leukemia.