The mitochondrial fractions of U251 control tissues show 68.49±0.42% (mean ± S.D.)of pEGFR whereas 5310 control tissues show about 53.72±2.21% of pEGFR, which means that out of total pEGFR present in these glioma tissues, major portion of activated EGFR is translocated to mitochondria (Fig. 7E). This evidence concerns the gene EGFR and central nervous system cancer.