In selected experiments we examined TGF-β and IL-10 intracellular production after malaria and schistosomal antigen stimulation in PBMC obtained from 8 SP children (4 SP Mal and 4 SP no Mal) and 6 SN Mal children with malaria, during the wet and dry season follow-up. The gene discussed is TGFB1; the disease is malaria.