TLR4 and bronchopulmonary dysplasia: The frequency of combined heterozygous/rare homozygous TLR4-299 genotype was greater in preterm neonates with moderate or severe BPD (n = 103) compared to preterm neonates without BPD (n = 62) used as a control group (12% versus 1.6%; p = 0.016; Table 2).