This remained true in primary (CD127+132−: 60% naïve, CD127+132+: 54%, CD127−132+:30%; p<0.001) and in chronic HIV infection (CD127+132−: 53% naïve, CD127+132+: 46%, CD127−132+:20%; p<0.05; Figure 1a)ii and b)ii). The gene discussed is IL7R; the disease is HIV infectious disease.