PPARA and inherited lipid metabolism disorder: Earlier studies on the association of PPARα Intron 7C polymorphism with dyslipidaemia in diabetic subjects have shown that variation in the PPARα gene influences total cholesterol, LDL-cholesterol (LDL-C), and HDL-cholesterol (HDL-C) in diabetic patients [10, 11] and that the C allele is associated with increased total cholesterol and LDL cholesterol [12].